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Borbath and coworkers [82] reported the case of a 51-year-old woman who received 10 mg/kg VPA daily to prevent seizures after a neurosurgical procedure, and who developed VHE (ammonia concentration 234 mol/l) without any sign of hepatic dysfunction

Meanwhile, GLP-1RAs showed a trend towards a reduced risk for nine respiratory diseases, although not reaching statistical significance, including pneumonia (RR 0.89, 95% CI 0.781.00, p = 0.05

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Patients should be aware that research in this area is ongoing, and long-term safety and efficacy data may be limited for certain therapies