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doi: 10.1111/j.1365-2265.1995.tb02929.x 103 RaunKHansenBSJohansenNLThogersenHMadsenKAnkersenMet al

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As a result, hepatocellular supplies of glutathione become exhausted and NAPQI is free to react with cellular membrane molecules, resulting in widespread hepatocyte damage and death, leading to acute hepatic necrosis