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3 The gastrointestinal side-effect profile seen across its trials is the clinical fingerprint of that mechanism
Sermorelin is a GHRH analog that stimulates the pituitary gland to produce and release its own GH through the body's natural regulatory pathway
doi: 10.1097/SHK.0000000000001869 415 ChenYHeWWeiHChangCYangLMengJet al
Receptor activation triggers a PLC-IP3-Ca2+ cascade leading to rapid pulsatile release of GH stored in secretion granules
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