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The absence of muscle-building effects means weight changes reflect primarily fat loss rather than mixed body recomposition
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Plasma levels of GHK are estimated at around 200 ng/mL at age 20 and decline steadily with age, which coincides with the slowdown in collagen production and wound repair that characterizes aging skin
The open question for regulators conducting the CagriSema FDA review is whether combining two appetite-suppressing mechanisms produces an additive gastrointestinal burden that alters the benefit-risk calculation in a market already offering several tolerable alternatives
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