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History of pancreatitis Patients with a history of severe or recurrent pancreatitis may not be appropriate candidates

After pre-incubation, cells were incubated in KRB buffer containing 2- or 16.8-mM glucose (Sigma-Aldrich) at 37 C for 30 min, respectively

In some cases, as with semaglutide in Wegovy, after a medication is approved and sold, other adverse events, called postmarketing experience are reported

This finding highlights a fundamental distinction that must be applied when interpreting the preclinical literature as a whole: the majority of studies reporting positive outcomes employed a preventive or co-treatment paradigm, in which the drug was administered prior to or concurrently with pathological induction