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By restoring systemic glutathione levels, patients can improve their cellular redox buffer, potentially increasing their tolerance for daily activities and reducing the severity of exertion-induced crashes
CRISPR-Cas9-mediated homology-donor repair was used to insert the yellow fluorescent protein Venus sequence, or the cAMP FRET-based reporter EpacS-H187 at the 3 end of the CCK coding sequence
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