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AMY1R, AMY2R, and AMY3R
Central GLP-1R activation in hypothalamic and mesolimbic pathways may lead to fatigue, lethargy, or brain fog 63 , though such effects might be often transient and dose-dependent
So your liver, now youre training your livers mitochondria
Management strategies: Eat smaller, more frequent meals Avoid high-fat, greasy, or heavily spiced foods initially Stay hydrated For constipation (common): increase fiber gradually, drink more water, consider magnesium supplement Ginger or peppermint tea for nausea Dont lie down immediately after eating (helps with reflux) Under-eating risk (serious for women over 40): The appetite suppression can be so strong that some women struggle to eat enough protein and calories to support muscle maintenance and basic metabolic function
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