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Whether synergistic, additive, or independent effects are produced in vivo depends on the specific research model, tissue type, and application method questions that remain open in the published literature for this specific blend ratio
The total reduction from baseline was greater, but some improvement also occurred with placebo
The main analysis was conducted in the primary cohort, and the exploratory cohort was used for sensitivity analysis
Ibuprofen should be used at the lowest effective dose for the shortest duration possible, typically no more than a few days for acute pain without medical supervision
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