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Sin embargo, el proceso presentaba problemas como el uso de sustancias txicas que contienen cianuro, el alto costo de los agentes de resolucin y los catalizadores, la dificultad para aprovechar la otra mitad del enantimero separado, los numerosos pasos de reaccin, el bajo rendimiento, los altos costos y el elevado precio del producto

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The investigators also identified oxidized forms in confiscated black-market products, indicating quality concerns in the gray-market supply