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While its still early days for a large-scale population study of how HRT and Ozempic interact, there is evidence that in tandem, the two are in effect a turbo-powered weight-loss solution: A scientific study published this year found that postmenopausal women using hormone replacement therapy and semaglutide had a higher total body weight loss at three, six, nine and 12-month markers than women using semaglutide alone

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