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In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]
The cardiovascular benefit of finerenone in CKD patients with diabetes was primarily attributable to the reduction in the risk of HHF and was similar in FINEARTS-HF for patients with HFpEF [54]
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