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Yet these same states also rank near the bottom for per capita income, pushing their GLP-1 income burden ratios above 12%, according to our analysis

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For instance, people who have a prescription for an injectable form of semaglutide might skip some doses because they dont like needles

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Notably, elevated plasma biomarker concentrations are linked to reduced white matter quality (Figure 3A and B), showing brain regions where GFAP and, to a smaller extent, NfL concentrations are amplified, affecting neurite density reduction and neuronal health processes

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(Research has identified mast cells as one of the immune cell types involved in the inflammatory cascades that influence arterial plaque development and lipid-related cardiovascular risk, as I note in my MCAS info page.) In neurological disease , research in animal models of stroke and vascular dementia has shown that GLP-1RAs reduce both microglial activation and neuroinflammation, leading to better protection of the brain from injury and cognitive deterioration

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