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Reviews from real Noom users The bottom line: The side effects of retatrutide are similar to Zepbound Retatrutide is shaping up to be one of the most promising next-generation weight loss medications, with early results that go beyond what weve seen from current GLP-1 and dual agonist options

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The glucagon receptor activation that drives heart rate increase also drives hepatic fat oxidation, which is a primary mechanism behind the lipid improvements