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(3) Inhibiting Adipose Tissue Inflammation and Improving the Adipose Microenvironment In obesity, adipose tissue develops chronic lowgrade inflammation with abundant release of proinflammatory factors (such as TNF and IL6), disrupting the adipose microenvironment, further worsening fat metabolic abnormalities and insulin resistance, and forming a vicious cycle

(2021) evaluated the cardiovascular benefits of GLP-1 RAs in patients with T2DM

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Viral mediated expression of IGF-1 blocks the aging-related loss of skeletal muscle function