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One of the conceptual turning-points regarding the significance of these compounds in plants occurred in the second half of the 1970s, when the ascorbateglutathione pathway was first characterized as a chloroplastic antioxidative process

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N-Acetyl-L-Cysteine (NAC) is a highly stable, bioavailable derivative of the conditionally essential amino acid L-cysteine

In this context, a series of tests was conducted to examine ROS generation, depolarization of mitochondrial membrane potential, DNA damage, and apoptosis in cultured E9 cells, a commonly used model for cardiovascular disease research