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Conversely, neither 3 weeks LC supplementation in healthy, recreationally weight-trained men [37], nor 24 weeks LC supplementation in aged women [15] did not affect circulating IGF-1 level concentration

The supply of such aminos, like l-carnitine, must be supplemented exogenously

Glasauer, A., Sena, L

Bottom Line Despite some dizzying progress for this class of drugs, there are still so many unknowns (besides lack of explainability as already touched on)