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The metabolism and skeletal development, bone density, and aging are all profoundly impacted by this hormone

Consistent with the notion that GSH export and degradation are elevated during cystine starvation, there was a greater accumulation of extracellular GSH when GGT was inhibited (Fig

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The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo