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2025 Jan- Al Amin ASM, Gupta V
Drop back to the last tolerated dose and stay there for 6-8 weeks before attempting escalation again
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771
NNMT is strongly associated with metabolic regulation, adiposity, glucose balance, and energy expenditure in animal models
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