A multilevel mixed-effects model was used to interrogate the repeated key secondary outcome measures at 24 weeks and 52 weeks
Neurochem Res 40:25272543 Higgins RD, Raju T, Edwards AD, Azzopardi DV, Bose CL, Clark RH, Ferriero DM, Guillet R, Gunn AJ, Hagberg H, Hirtz D, Inder TE, Jacobs SE, Jenkins D, Juul S, Laptook AR, Lucey JF, Maze M, Palmer C, Papile L, Pfister RH, Robertson NJ, Rutherford M, Shankaran S, Silverstein FS, Soll RF, Thoresen M, Walsh WF (2011) Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop
That said, you need to know how to use them properly and what effects you can anticipate as a result
Retinoids: Generally, it's best to alternate nights or use CPs in the AM and Retinoids in the PM to avoid potential irritation from layering too many potent actives