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These structural modifications enable it to activate GLP-1, GIP, and glucagon receptors whilst resisting enzymatic breakdown and maintaining a long circulating half-life
Gullaksen S, Vernstrm L, Srensen SS, et al
About half of Americans are concerned about long-term effects Nearly half of Americans (46%) who are aware of GLP-1 drugs are very or extremely concerned about their long-term health effects, which increases to 51% for those taking the medications
More patients are beginning to talk about the emotional side effects of semaglutide , reporting unexpected mood changes, anxiety, or even symptoms of depression
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