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During aging, metabolic function gradually declines, leading to insulin resistance, fat accumulation, and insufficient energy metabolism

In laboratory settings, DSIP is applied in biochemical assays, EEG-based sleep studies, and preclinical models to explore how peptide signaling influences central nervous system function and stress-response mechanisms

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P450 enzymes are also involved in the first step of the methylation pathway, where they convert methionine to S-adenosylmethionine (SAMe)