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Microdosing a GLP-1 (aka Ozempic, Wegovy, semaglutide, tirzepatide, zepbound, etc) is taking a lower than the lowest granular dose prescribed by the FDA for weight loss, but some people use it interchangeably when referring to one of the smaller doses on the dosing schedule
Previous physiological studies have shown that both GIP (113116) and GLP-1 (117) act in concert with glucose to enhance insulin gene transcription, mRNA stability, insulin biosynthesis, and insulin secretion
A recent retrospective cohort also observed that, even in overweight patients without diabetes, the risk of primary open-angle glaucoma and ocular hypertension were significantly lower in the GLP-1RA group at both 3 and 5 years of follow-up (Vasu et al., 2025), suggesting the benefit of GLP-1RAs in the eye as an independent factor apart from blood glucose control
Here it is: 9mg or 12mg refer to separate maintenance dosing endpoints or a titration step if you plan on 12mg
