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If symptoms persist beyond the early titration period, temporary dose stabilization or dose reduction should be considered
Bonacini M, Kassamali F, Kari S, Lopez Barrera N, Kohla M
The studys primary endpoints were changes from baseline in glycated hemoglobin (HbA1c, a marker of long-term blood sugar levels) and total body weight at 182.5 days and 365 days post-initiation
Tolerability was managed through the standard 4-step dose escalation protocol starting at 1.5 mg/week
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