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Properly administered at suitable doses, its generally safe, with mild and transient side effects such as injection site reactions and water retention
Akkermansia genus was associated with increased DKD risk (OR = 1.45, 95% CI: 1.181.79), while Dialister genus and Proteobacteria phylum showed protective effects
Either a vascular obstruction (ischemic stroke in over 80% of cases) or a vascular rupture with bleeding within the brain (hemorrhagic stroke) are the offending mechanisms
Epidemiology More than seventy patients have been reported in more than 50 families worldwide
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