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According to NICE guidance (NG28), GLP-1 agonists are recommended for adults with type 2 diabetes who have not achieved adequate glycaemic control with other therapies
Potential Benefits and Risks of Combining These Approaches The primary benefit is metabolic efficiency: tirzepatide reduces calorie intake through appetite suppression, while fasting extends the time your body burns stored fuel
73 In patients with reflux-predominant symptoms unresponsive to lifestyle modification, proton pump inhibitors or histamine-2 receptor antagonists may be used
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