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He felt nausea and constipation in the early days
A severe or prolonged B12 deficiency can cause severe neurological dysfunction and contribute to osteoporosis
Tests in bacteria, cells, and mice all came back negative, suggesting the compound does not pose carcinogenic risk through DNA damage mechanisms
Although brain infarction volume reduction did not reach statistical significance, motor performance in the rotarod test significantly recovered in DSIP-treated animals compared to vehicle controls confirming a functionally relevant neuroprotective effect at the behavioural level and establishing intranasal delivery as a viable route for CNS DSIP research
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