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Nausea and diarrhoea were the most common side effects which were transient and improved with time, with less than 5% TLDR summary: The SUSTAIN 6 trial looked at the cardiovascular outcomes (cardiovascular death, heart attack and stroke) in high cardiovascular risk diabetic patients being treated with semaglutide versus placebo- with the results showing a significant 26% reduction in cardiovascular death, heart attack and stroke in patients being treated with semaglutide The SUSTAIN 6 trial published in the New England Journal of Medicine showed that in patients with type 2 diabetes who were at high cardiovascular risk
Macrolide antibiotics such as Zithromax (azithromycin)
Patients taking metformin along with tirzepatide may be at increased risk for vitamin B12 deficiency, which can cause fatigue
Andrew Hardaway, Ph.D
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