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Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice

Promising therapeutics include semaglutide (Ozempic and Wegovy ), an agonist for glucagon-like peptide-1 (GLP-1) receptor, and tirzepatide (Mounjaro ), a dual agonist for GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

Lets dive into what we know so far about GLP-1 drugs and their potential impact on Rheumatoid arthritis (RA), Psoriasis, and Psoriatic arthritis(PsA)

The SURMOUNT-5 head-to-head trial compared tirzepatide directly against semaglutide in patients with obesity