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in fact, it is the most common GST expressed outside the liver
As a result, Nrf2 escapes degradation and translocate to the nucleus, where it binds to Antioxidant Response Elements (AREs) within the promoter regions of target genes
A meta-analysis of seven randomized controlled trials, including 441 participants, showed a significant, 2% increase with nicotinic acid (1-2 g/day) administered for 12 weeks to one year (86)
A note on the bigger question first Glutathione is an antioxidant the body makes naturally
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