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It works by: Blocking the reuptake of serotonin in the brain, increasing the availability of this neurotransmitter in the synaptic space Enhancing serotonergic neurotransmission , which helps regulate mood, anxiety, and emotional responses Sertraline is taken orally, typically once daily, and is metabolised in the liver by multiple cytochrome P450 enzymes, including CYP2B6, CYP2C19, CYP2D6, and CYP3A4

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Analysts estimate the submission could come in Q4 2026 or early 2027, with potential approval in the 2027 to 2028 window if the timeline holds

The most up-to-date formulary information can be found on our Drug Formularies page here