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Quantitatively grounded SWOT
In some cases, a replacement may be available
In this double-blind trial of 1,961 adults with a body mass index (BMI) of 30 or higher, adults on high dose 2.4 mg of weekly semaglutide (compared with the usual type 2 diabetes dose of 0.5mg or 1mg) lost an average 14.9% of baseline body weight after 68 weeks of treatment versus only 2.4% for a group on placebo and lifestyle intervention alone
Exenatide may still serve a role in cost-constrained settings or when newer agents are unavailable, but semaglutide is the clear standard of care for new GLP-1 agonist prescriptions
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