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Thus, a number of studies have shown a positive association between plasma DPP-4 activity and BMI in non-diabetic individuals (7880), and it has been proposed that the release of DPP-4 from adipose tissue may provide one explanation for the increased plasma DPP-4 activity measured in obese subjects

Consistent reductions were seen for patients stratified by gender, age group, race and in patients with and without T2D