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Circulation 127(1):7485
Conclusion Switching from tirzepatide to retatrutide can absolutely make sense for some people especially if youve done well on tirzepatide but feel ready for a next step in your weight-loss and metabolic-health journey
Human epidemiological data from a 2023 pharmacovigilance study (N=1.3 million patient-years of GLP-1 exposure) did not show a significantly elevated MTC incidence, though the authors noted follow-up duration may be insufficient to detect a rare long-latency malignancy [9]
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