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145 demonstrated that various flavonoids, including quercetin, kaempferol, apigenin, rutin, and baicalein, stimulate CCK secretion from intestinal endocrine secretin tumor cell line cells in vitro , although their effectiveness varies

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Subsequently, numerous studies have emerged linking UA to neurodegenerative diseases (see Table 1)

We postulated that a BETP-sensitized assay would prove effective for identifying weak agonists and were pleased to observe potentiation of GLP-1R-mediated cAMP signaling in response to the weak non-peptide GLP-1R agonist BOC5 ( 24 ) (Fig