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This enzyme is often overexpressed in adipose tissue in conditions of obesity and metabolic dysfunction, leading to the depletion of nicotinamide and reduced availability of NAD+
Autoimmune and neurologic conditions Conditions like multiple sclerosis (MS) can cause episodic numbness
Common reactions may include pain, redness, or irritation at the injection site, mild diarrhea, nausea, itching, headache, dizziness, or a general feeling of swelling
TB-500 also appears to be generally well-tolerated, but again, safety data derived from adequately powered clinical trials is lacking
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