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Twice daily application: Most copper peptide products recommend twice-daily use, and this frequency appears safe and potentially beneficial for most skin types
What the literature actually describes is better summarized as copper-dependent enzyme cofactor logistics: the complex participates in the movement of copper between ligands of differing affinity, and the downstream observations follow from where the copper ends up
10.1016/j.biomaterials.2012.12.009 Biomaterials 7 CharlierE.DeroyerC.CiregiaF.MalaiseO.NeuvilleS.PlenerZ.et al (2019)
The glycine component contributes to extending this stability window by maintaining pH and preventing aggregation throughout the use period
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