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Direct addition of SANA to BAT-isolated mitochondria also had no effect on GDP-inhibited respiration (Extended Data Fig

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Results Identification of C1-27 as a potent GSTO1 inhibitor The -chloroacetamide is a privileged scaffold that has been commonly used to target cysteine residues on various proteins 20,21,25

This doesn't necessarily mean DSIP is dangerous, but it does mean comprehensive safety evaluation hasn't been completed