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of participants with at least one outcome event) of nausea, vomiting, diarrhoea, treatment discontinuation due to gastrointestinal events, severe adverse events and severe hypoglycaemia (a hypoglycaemic event requiring assistance)

Lab tests may also help identify if the reason behind the weight loss is another underlying condition, such as thyroid disease

6,7 ACE=angiotensin-converting enzyme

Beginning in 2008, extensive cardiovascular outcome trials (CVOTs) were conducted to evaluate the safety and efficacy of novel glucose-lowering agents