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Results MOTS-c declines with chronological aging in pancreatic -cells The coding sequence for the mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) is located within the 12S rRNA gene (mtRNR1) of mtDNA 6,7,8,10 and is closely linked to aging 9
Multiple controlled trials using indirect calorimetrythe gold standard for measuring energy expenditurehave demonstrated that GLP-1 therapy does not elevate RMR beyond what would be expected from changes in body composition
Effects of treatment for diabetes mellitus on testosterone concentrations: A systematic review 5
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