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Major characteristics include infantile lethargy and hypotonia causing poor feeding and failure to thrive, developmental and intellectual disability, hypogonadism (small external genitalia and pubertal insufficiency), hyperphagia leading to morbid obesity if uncontrolled, short stature, characteristic facial appearance and body habitus, and a typical behavioral phenotype that includes temper tantrums and compulsive traits

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This is why small molecule alternatives deserve serious attention from anyone thinking about GLP1 access at population scale

Microdosing simply means taking less than is typically prescribed