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In the STEP 1 trial extension phase, participants who discontinued semaglutide regained approximately two-thirds of their lost weight within one year
Both drugs may be prescribed for people with obesity with a body mass index (BMI) of 30 or higher and people who are overweight with a BMI of 27 or higher with weight-related medical conditions
705-11, PMID 8797468
According to the American Diabetes Association (ADA), GLP-1 receptor agonists are now recommended as a first-line treatment in certain high-risk patients, especially those with established cardiovascular disease
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