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The FDA has documented cases where patients experienced symptoms lasting several days after accidental overdoses
The molecular mechanisms primarily involve excessive activation of the unfolded protein response triggered by endoplasmic reticulum stress in granulosa cells [350], leading to caspase cascade-dependent apoptosis, as well as DNA strand breaks and membrane lipid peroxidation induced by mitochondrial electron transport chain leakage in spermatozoa [351, 352]
Many patients continue taking semaglutide until they reach their desired weight, with guidance from our health experts to monitor progress and determine when to stop
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