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Our results show that serum biochemical parameters related to liver function changed significantly in the groups that were given flunixin meglumine (FM) alone and FM combined with alpha-lipoic acid (ALA).We observed significant increases in the levels of alanine aminotransaminase (ALT), aspartate aminotransaminase (AST), and alkaline phosphatase (ALP) in groups that received FM at dosages of 2.5 and 5 mg/kg bwt for 14 consecutive days, respectively, compared to the control group