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In addition, MCTH NCs composed of disulfide (S-S) doped mesoporous organosilica (MONs), copper-modified porphyrin (CuPpIX), mitochondria-targeted triphenylphosphine (TPP), and CD44-targeted hyaluronic acid, can efficiently accumulate at tumor sites, significantly enhance CD8 + T cell infiltration into tumors thereby achieving potent antitumor acoustic immunotherapy (161)
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