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The consequences of NNMT inhibition over months or years are unknown
Visible Aging: This is often when the very first fine lines or changes in skin tone begin to appear, which are often signs of oxidative stress
Moreover, ischemic conditions can trigger the release of Ca 2+ from intracellular stores, such as the endoplasmic reticulum, worsening the situation by contributing to intracellular calcium overload
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