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doi:10.1074/jbc.M209372200
It establishes a robust yet adaptable coordination with Cu(II) ions, utilizing the amino group of glycine, the imidazole nitrogen of histidine, and the -amino group of lysine
Rather than advancing to the next dose level every four weeks, extend each dose phase to six or eight weeks to allow more thorough adaptation
As I notes in the Straits Times: "This is a major breakthrough reflecting Chinas progress in closing the biopharma innovation gap
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