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These project to adjacent A2 cells in the NTS and are involved in the decreased food intake associated with anorexic agents such as lithium chloride and cholecystokinin (65, 66)

However, there have been indications that regular doses of 1 g over extended periods, such as months or years, may reduce bactericidal activity in leukocytes and increase the risk of stone formation caused by temporary urate excretion elevation

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