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The exact mechanism is not confirmed, but retatrutide's triple-receptor activity targeting GLP-1, GIP, and glucagon receptors may influence neuroimmune and vasodilatory pathways that affect skin physiology
Projections have been mapped between the VTA and LSc (51), and acute stimulation of GLP-1Rs in the LSc leads to enhanced LSc dopamine transporter surface expression and function
Our guide to getting the Wegovy pill on the NHS explains this in more detail
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