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If total calories drop to 1,400 per day, protein should account for 400 to 600 of those calories
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Reactive oxygen species (ROS), produced via GSH-mediated pathways, can serve as danger-associated molecular patterns, stimulating dendritic cells and promoting T-cell expansion [82]
Consequently, SURMOUNT-MAINTAIN demonstrated that while MTD allowed for 100% weight loss maintenance, dose reduction to 5mg provided 70% weight loss maintenance, representing a clinically viable and statistically superior alternative to treatment discontinuation
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