For one, the higher the dosage, the more at risk you are for the most common Wegovy side effects, which include nausea, constipation, and vomiting
Under NICE guidance (TA664), Saxenda is available on the NHS only through specialist weight management services for people who meet specific criteria: a BMI of at least 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, Black African or African-Caribbean backgrounds) with weight-related comorbidities, and only as part of a comprehensive programme including diet, physical activity and behavioural support
There is no prior authorization, step therapy, or utilization management
Many of the changes in lipid profiles related to obesity overlap with diabetic dyslipidemia including increased triglycerides, increased very-low-density lipoprotein (VLDL), increased small density LDL-C, and decreased HDL-C [18]